Oral etoposide in oncology: An evolving role

Attenuation of tumor growth by honokiol: an evolving role in oncology.

Honokiol may exert significant antineoplastic effects in other systemic tumors besides skin cancers by virtue of modulation of other pathways. For instance, honokiol attenuates tumor growth in mammary malignancies. It mediates its anti-neoplastic role in these tumors by accentuating the phosphorylation of AMPK. As a result, honokiol causes significant mitigation of tumor proliferation and growth.

An Emerging Role for Radiation Oncology in Precision Oncology

Article history: Received 1 March 2016 Accepted 1 March 2016 Available online 4 March 2016 the precision of radiotherapy delivery (e.g. computational algorithms, IMRT, IGRT, SBRT); and3. Incorporationof novel radiosensitizing andmolecular targeting agents with radiation therapy to reduce mechanisms of radiation resistance (e.g. epithelial growth factor receptor inhibitors and RT in head and nec...

Ubiquitination — An Evolving Role in DNA Repair

Refractory Choriocarcinoma: Complete Response With Oral Etoposide

A 33-year-old, married woman came to the hospital in 2015 with bleeding from the vagina and shortness of breath of 3 months’ duration. Her obstetric history was as follows: the first pregnancy ended in a miscarriage, the second was a stillbirth, and the third was a molar pregnancy. She delivered a healthy girl after her fourth pregnancy 4 years ago. At presentation, her beta human chorionic gon...

The Evolving Role of Physicians - Don’t Forget the Generalist Primary Care Providers; Comment on “Non-physician Clinicians in Sub-Saharan Africa and the Evolving Role of Physicians”

The editorial “Non-physician Clinicians in Sub-Saharan Africa and the Evolving Role of Physicians” by Eyal et al describes non-physician clinicians’ (NPC) need for mentorship and support from physicians. We emphasise the same need of support for front line generalist primary healthcare providers who carry out complex tasks yet may have an inadequate skill mix.